Hyperbaric oxygen therapy for brain injury, cerebral palsy, and stroke.

s and Conference Proceedings Three trials 100, 101 and four observational studies that included only TBI patients were reported only as meeting abstracts or conference proceedings (Evidence Table 7). One trial reported improvements in at least some neurologic or functional outcomes, based on an undefined scale. The other trial classified each patient’s outcome as a “cure,” a “marked effect,” a “positive effect,” “no effect,” or death. Cure was defined as “conscious, symptoms disappeared, and can care for self.” Twenty-two of 32 (69 percent) in the HBOT group were cured, compared to 9 of 15 (36 percent) in the control group (p < 0.05). The two observational studies were not reported in full. 103 The lengths of followup were not clear and there was insufficient information to rate the quality of these studies. Both reported improvements, one using the GCS (however, no data were reported), and one using the digital symbol test (a mean 12.2-point improvement). Other Nontraumatic Brain Injury